One thing that I use almost every minute is the Windows Run box (WINDOWS+R). It let's you type a path and auto-completes it really quickly so that you can jump to any dir in no time.
My problem is that I recently swapped disks and re-organized content so a few of the drive letters changed while most (but not all) the dir structure stayed the same. Now the auto-complete is giving me a lot of old results that don't physically exist anymore and it's not only annoying but the advantage of speed is not there anymore because I now have to check for old results in my auto-complete!
How can I clear that auto-complete's cache?
EDIT: I'm not talking about how to clear the last run items from the Windows Start menu. This is completely different. What I'm talking about auto-completes directories in the file system and is "remembering" old auto-completed paths (which are NOT programs, just paths).